Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NB500-309
Clone MEM-83 was used by HLDA to establish CD designation.
![Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309]](https://resources.bio-techne.com/images/products/nb500-309_mouse-monoclonal-integrin-alpha-l-cd11a-antibody-mem-83-13120241649370.jpg "Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry, Immunoprecipitation
Cited:
Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # MEM-83
Format
BSA Free
Concentration
1.0 mg/ml
Product Specifications
Immunogen
Human peripheral blood lymphocytes.
Specificity
The antibody MEM-83 reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. HLDA IV; WS Code N 211
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Theoretical MW
180 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free
Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309]
Surface staining pattern of human peripheral blood cells stained using anti-human CD11a (MEM-83) purified antibody (concentration in sample 1 ug/ml) GAM APC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309] -
Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309] - Surface staining pattern of human peripheral blood cells stained using anti-human CD11a (MEM-83) purified antibody (low endotoxin, concentration in sample 1 ug/ml) GAM APC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309] -
Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free [NB500-309] - Surface staining pattern of human peripheral blood cells stained using anti-human CD11a (MEM-83) purified antibody (low endotoxin, concentration in sample 1 ug/ml) GAM APC.Applications for Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free
Application
Recommended Usage
Flow Cytometry
1 ug/ml
Immunoprecipitation
1:50
Application Notes
Functional Application: The antibody MEM-83 directly induces the binding of T cells to purified ICAM-1. Using an in vitro-translated CDlla cDNA deletion series, the MEM-83 activation epitope was mapped to the "I" domain of the LFA-1 alpha subunit. The studies have therefore identified a novel LFA-1 activation epitope mapping to the I domain of LFA-1, which could play a role in the regulation of LFA-1 binding to ICAM-1.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH 7.4)
Format
BSA Free
Preservative
0.9% Sodium Azide
Concentration
1.0 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: Integrin alpha L/CD11a
Alternate Names
CD11a, ITGAL, LFA-1 alpha, Ly-15, Ly-21
Entrez Gene IDs
3683 (Human)
Gene Symbol
ITGAL
Additional Integrin alpha L/CD11a Products
Product Documents for Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free
Product Specific Notices for Integrin alpha L/CD11a Antibody (MEM-83) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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