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Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97563

Clone VIPL2 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP1-97563
Conjugate
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Key Product Details

Species Reactivity

Validated:

Human, Primate

Cited:

Human

Applications

Validated:

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # VIPL2

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

The mouse monoclonal antibody VIPL2 recognizes CD61

Specificity

The mouse monoclonal antibody VIPL2 recognizes CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free

Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563] - SUM159PT cells were stained with Integrin beta 3/CD61 antibody (NB100-64861AF488, 0.5 ug/10^6 cells). Left: unstain; Right: ITGB3 antibody stain. Image from verified customer review.
Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: CD41/CD61 Antibody (VIPL2) [NBP1-97563] - Staining of human peripheral blood with anti-human CD61 (VIPL2) PE-CyTM7.
Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free [NBP1-97563]

Flow Cytometry: CD41/CD61 Antibody (VIPL2) [NBP1-97563] - Staining of human peripheral blood with anti-human CD61 (VIPL2) APC.

Applications for Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:200

Western Blot

1:1000
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin beta 3/CD61

CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.

Alternate Names

CD61, GP3A, GPIIIA, INGRB3, ITGB3

Gene Symbol

ITGB3

Additional Integrin beta 3/CD61 Products

Product Documents for Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin beta 3/CD61 Antibody (VIPL2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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