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Integrin beta 6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14136

Novus Biologicals, part of Bio-Techne
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NBP2-14136
NBP2-14136-25ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: RGDCVCGKCVCTNPGASGPTCERCPTCGDPCNSKRSCIECHLSAAGQAREECVDKCKLAGATISEEEDFSKDGSVSCSLQGENECLITFLITTDNEGKTIIHSI

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 24305999). Rat (88%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin beta 6 Antibody

Immunocytochemistry/ Immunofluorescence: Integrin beta 6 Antibody [NBP2-14136]

Immunocytochemistry/ Immunofluorescence: Integrin beta 6 Antibody [NBP2-14136]

Immunocytochemistry/Immunofluorescence: Integrin beta 6 Antibody [NBP2-14136] - Staining of human cell line RT4 shows localization to nucleoplasm & cell junctions. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Integrin beta 6 Antibody [NBP2-14136]

Immunohistochemistry-Paraffin: Integrin beta 6 Antibody [NBP2-14136]

Immunohistochemistry-Paraffin: Integrin beta 6 Antibody [NBP2-14136] - Staining of human rectum shows strong cytoplasmic and membranous positivity in granular pattern in glandular cells.

Applications for Integrin beta 6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin beta 6

Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion

Alternate Names

ITGB6

Gene Symbol

ITGB6

Additional Integrin beta 6 Products

Product Documents for Integrin beta 6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin beta 6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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