IP3R1 Antibody (4Z1B6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16414

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16414-100ul
NBP3-16414-20ul
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4Z1B6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IP3R1 Antibodies »

Product Summary for IP3R1 Antibody (4Z1B6)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 2200-2300 of human IP3R1 (Q14643). HTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVA

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IP3R1 Antibody (4Z1B6)

Western Blot: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Western Blot: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Western Blot: IP3R1 Antibody (4Z1B6) [NBP3-16414] - Western blot analysis of extracts of Mouse brain, using IP3R1 Rabbit mAb (NBP3-16414) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunohistochemistry: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Immunohistochemistry: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Immunohistochemistry: IP3R1 Antibody (4Z1B6) [NBP3-16414] - Immunofluorescence analysis of mouse brain using IP3R1 Rabbit mAb (NBP3-16414) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry-Paraffin: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Immunohistochemistry-Paraffin: IP3R1 Antibody (4Z1B6) [NBP3-16414]

Immunohistochemistry-Paraffin: IP3R1 Antibody (4Z1B6) [NBP3-16414] - Immunohistochemistry of paraffin-embedded rat brain using IP3R1 Rabbit mAb (NBP3-16414) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
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Applications for IP3R1 Antibody (4Z1B6)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IP3R1

IP3R1 (inositol 1,4,5-triphosphate receptor type 1) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian InsP3R receptors: Insp3R1, Insp3R2, and Insp3R3. Defects in the gene which encodes InsP3R1, ITPR1, are the cause of spinocerebellar ataxia type 15 (SCA15).

Long Name

Inositol 1,4,5-trisphosphate receptor type 1

Alternate Names

InsP3R1, IP3R 1, ITPR1

Gene Symbol

ITPR1

Additional IP3R1 Products

Product Documents for IP3R1 Antibody (4Z1B6)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IP3R1 Antibody (4Z1B6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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