IRF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1089

Novus Biologicals, part of Bio-Techne
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NB100-1089
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Canine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all IRF2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence KTSDITQARVKSC corresponding to C-Terminus according to NP_002190.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for IRF2 Antibody

Western Blot: IRF2 Antibody [NB100-1089]

Western Blot: IRF2 Antibody [NB100-1089]

Western Blot: IRF2 Antibody [NB100-1089] - Staining (2ug/ml) of Jurkat lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for IRF2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

1 - 3 ug/ml
Application Notes
Approx 48kDa band observed in lysates of cell line Jurkat (calculated MW of 39.3kDa according to NP 002190.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Li et al, Invest Ophthalmol Vis Sci. 1999 Apr, 40(5):976-82., PMID: 10102295. Recommended concentration: 1-3ug/ml.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IRF2

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Long Name

Interferon Regulatory Factor 2

Alternate Names

DKFZp686F0244, interferon regulatory factor 2, IRF-2

Entrez Gene IDs

3660 (Human); 16363 (Mouse)

Gene Symbol

IRF2

UniProt

NP_002190 (Human)

Additional IRF2 Products

Product Documents for IRF2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IRF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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