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IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14228

Novus Biologicals, part of Bio-Techne
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NBP3-14228

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # PCRP-IRF9-2F8

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant full-length human IRF9 protein (Uniprot: Q00978)

Localization

Cytoplasm, Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

43.34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-13835).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free

Protein Array: IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free [NBP3-14228]

Protein Array: IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free [NBP3-14228]

Protein Array: IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free [NBP3-14228] - Analysis of Protein Array containing more than 19,000 full-length human proteins using IRF9 Antibody (PCRP-IRF9-2F8).

Applications for IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1-2 ug/million cells

Immunocytochemistry/ Immunofluorescence

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: IRF9

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state

Long Name

Interferon Regulatory Factor 9

Alternate Names

ISGF3, ISGF3G

Gene Symbol

IRF9

Additional IRF9 Products

Product Documents for IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IRF9 Antibody (PCRP-IRF9-2F8) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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