ITPR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49294

Novus Biologicals, part of Bio-Techne
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NBP2-49294
NBP2-49294-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ITPR2 Antibodies »

Product Summary for ITPR2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTC

Reactivity Notes

Mouse (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ITPR2 Antibody

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294] - Staining of human skin shows weak cytoplasmic positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294] - Staining of human parathyroid gland shows cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294]

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP2-49294] - Staining of human kidney shows moderate to strong granular cytoplasmic positivity in cells in tubules.
View 1 more images

Applications for ITPR2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITPR2

Inositol 1,4,5-triphosphate (IP3) receptors are a form of ligand-gated ion channels that are activated by cytosolic Ca2+ and IP3. They are localized to intracellular membranes, such as the endoplasmic reticulum, and mediate the mobilization of intracellular Ca2+ stores. IP3 receptors play an important role in intracellular Ca2+ signaling in a variety of cell types. There are three IP3 receptor subtypes; IP3R1, IP3R2 and IP3R3, which exist as homo- and heterotetramers. All subtypes are closely associated with calmodulin and FK506-binding protein and are modulated through phosphorylation by PKA, PKC, PKG and CaMKII.

Long Name

Inositol 1,4,5-trisphosphate receptor type 2

Alternate Names

InsP3R2, IP3R 2

Gene Symbol

ITPR2

Additional ITPR2 Products

Product Documents for ITPR2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ITPR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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