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Jagged 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86337

Novus Biologicals, part of Bio-Techne
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NBP1-86337
NBP1-86337-25ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LVVIPFQFAWPRSFTLIVEAWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYS

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 27183608).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Jagged 2 Antibody

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337] - Staining of human cervix, uterine shows moderate membranous positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337] - Staining of human placenta shows strong membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337]

Immunohistochemistry-Paraffin: Jagged 2 Antibody [NBP1-86337] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

Applications for Jagged 2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Frozen

Reported in scientific literature (PMID 27183608)

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Jagged 2

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Alternate Names

HJ2, JAG2

Gene Symbol

JAG2

Additional Jagged 2 Products

Product Documents for Jagged 2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Jagged 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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