Jagged 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27420

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-27420
NBP2-27420SS
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Primate

Predicted:

Equine (94%), Monkey (100%), Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Jagged 2 Antibodies »

Product Summary for Jagged 2 Antibody

Immunogen

A portion of amino acids 150-210 of human JAG2 was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in monkey, 94% homologous in mouse, rat and horse, 76% homologous in opossum and 70% homologous in chicken.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Jagged 2 Antibody

Western Blot: Jagged 2 Antibody [NBP2-27420]

Western Blot: Jagged 2 Antibody [NBP2-27420]

Western Blot: Jagged 2 Antibody [NBP2-27420] - Analysis of JAG2 in mouse thymus lysate using 1) prebleed at 1:5000 dilution and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for Jagged 2 Antibody

Application
Recommended Usage

Western Blot

5-10ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Jagged 2

Protein jagged-2 (JAG2)is a Notch signaling pathway protein which is a ligand for Notch-1. It is a single-pass type 1 membrane protein which contains one DSL domain, sixteen EGF-like domains and one VWFC domain. JAG2, along with JAG1, DLL3 and DLL1 act as predominant Notch ligands, which have overlapping receptor binding specificities. JAG2 is also reported to regulating the expression of cytokines that can promote antitumor immunity.

Alternate Names

HJ2, JAG2

Gene Symbol

JAG2

UniProt

Q9Y219 (Human)

Additional Jagged 2 Products

Product Documents for Jagged 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Jagged 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.