JMJD2D Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47413

Novus Biologicals, part of Bio-Techne
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NBP2-47413
NBP2-47413-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all JMJD2D Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRAAAVHSSKKPSSTPSSTPGPSAQIIHPSN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JMJD2D Antibody

Immunocytochemistry/ Immunofluorescence: JMJD2D Antibody [NBP2-47413]

Immunocytochemistry/ Immunofluorescence: JMJD2D Antibody [NBP2-47413]

Immunocytochemistry/Immunofluorescence: JMJD2D Antibody [NBP2-47413] - Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: JMJD2D Antibody [NBP2-47413]

Immunohistochemistry-Paraffin: JMJD2D Antibody [NBP2-47413]

Immunohistochemistry-Paraffin: JMJD2D Antibody [NBP2-47413] - Staining of human testis shows moderate nuclear positivity in subset of cells in seminiferus ducts.

Applications for JMJD2D Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JMJD2D

JMJD2 is a member of the family of novel JmjC domain-containing histone demethylation (JHDM) enzymes, which has been shown to perform the enzymatic removal of methyl groups from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Histone demethylase activity has been linked to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation.

Long Name

Lysine-specific demethylase 4D

Alternate Names

JHDM3D, KDM4D

Gene Symbol

KDM4D

Additional JMJD2D Products

Product Documents for JMJD2D Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for JMJD2D Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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