JNK1/JNK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13296

Novus Biologicals, part of Bio-Techne
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NBP3-13296
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Mouse (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all JNK1/JNK2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human JNK1/JNK21 + JNK1/JNK22. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for JNK1/JNK2 Antibody

Western Blot: JNK1/JNK2 Antibody [NBP3-13296]

Western Blot: JNK1/JNK2 Antibody [NBP3-13296]

Western Blot: JNK1/JNK2 Antibody [NBP3-13296] - Various whole cell and tissue extracts were separated by 10% SDS-PAGE, and the membrane was blotted with JNK1/JNK2 antibody (NBP3-13296) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: JNK1/JNK2 Antibody [NBP3-13296]

Immunohistochemistry-Paraffin: JNK1/JNK2 Antibody [NBP3-13296]

Immunohistochemistry-Paraffin: JNK1/JNK2 Antibody [NBP3-13296] - JNK1/JNK2 antibody detects JNK1/JNK2 protein at cytoplasm and nucleus by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. JNK1/JNK2 stained by JNK1/JNK2 antibody (NBP3-13296) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Western Blot: JNK1/JNK2 Antibody [NBP3-13296]

Western Blot: JNK1/JNK2 Antibody [NBP3-13296]

Western Blot: JNK1/JNK2 Antibody [NBP3-13296] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with JNK1/JNK2 antibody (NBP3-13296) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for JNK1/JNK2 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JNK1/JNK2

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

Long Name

C-Jun N-terminal Kinase

Alternate Names

c-Jun N-terminal kinase 1, JNK, JNK1, JNK1A2, JNK21B1/2, JNK-46, JUN N-terminal kinase, MAP kinase 8, mitogen-activated protein kinase 8, PRKM8, SAPK1, SAPK1C, Stress-activated protein kinase 1, stress-activated protein kinase 1c

Gene Symbol

MAPK8

Additional JNK1/JNK2 Products

Product Documents for JNK1/JNK2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for JNK1/JNK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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