KALRN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-41371

Novus Biologicals, part of Bio-Techne
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NB100-41371
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Key Product Details

Species Reactivity

Validated:

Human, Mammal

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all KALRN Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RWHLGPGDPFSTYV, from the C Terminus of the protein sequence according to NP_003938.1; NP_001309918.1; NP_001309919.1; NP_001309920.1; NP_001309921.1.

Reactivity Notes

Mammal reactivity reported from a verified customer review.

Specificity

This antibody is expected to recognise NP_003938.1 (isoform 2), NP_001309918.1 (isoform 5), NP_001309919.1 (isoform 6), NP_001309920.1 (isoform 7), and NP_001309921.1 (isoform 8).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for KALRN Antibody

Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371]

Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371]

Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371] - Negative Control showing staining of paraffin embedded Human Cortex, with no primary antibody.
Flow Cytometry: KALRN Antibody [NB100-41371]

Flow Cytometry: KALRN Antibody [NB100-41371]

Flow Cytometry: KALRN Antibody [NB100-41371] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371]

Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371]

Immunohistochemistry-Paraffin: KALRN Antibody [NB100-41371] - Staining of paraffin embedded Human Cortex. Antibody at 5 ug/mL. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for KALRN Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/mL

Immunohistochemistry

4 - 5 ug/mL

Immunohistochemistry-Paraffin

4 - 5 ug/mL

Peptide ELISA

Detection Limit 1:16000

Reviewed Applications

Read 1 review rated 5 using NB100-41371 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: KALRN

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Alternate Names

ARHGEF24, DUETFLJ16443, DUO, EC 2.7.11.1, FLJ12332, FLJ18623, HAPIP, huntingtin-associated protein interacting protein (duo), Huntingtin-associated protein-interacting protein, Kalirin, kalirin, RhoGEF kinase, Protein Duo, serine/threonine kinase with Dbl- and pleckstrin homology domains, Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, TRADFLJ18196

Entrez Gene IDs

8997 (Human); 545156 (Mouse); 84009 (Rat)

Gene Symbol

KALRN

UniProt

O60229 (Human)

Additional KALRN Products

Product Documents for KALRN Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for KALRN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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