Katanin p60 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89491

Novus Biologicals, part of Bio-Techne
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NBP1-89491
NBP1-89491-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Katanin p60 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Katanin p60 Antibody

Immunocytochemistry/ Immunofluorescence: Katanin p60 Antibody [NBP1-89491]

Immunocytochemistry/ Immunofluorescence: Katanin p60 Antibody [NBP1-89491]

Immunocytochemistry/Immunofluorescence: Katanin p60 Antibody [NBP1-89491] - Staining of human cell line U-251 MG shows localization to nucleoplasm & microtubule organizing center. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Katanin p60 Antibody [NBP1-89491]

Immunohistochemistry-Paraffin: Katanin p60 Antibody [NBP1-89491]

Immunohistochemistry-Paraffin: Katanin p60 Antibody [NBP1-89491] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Applications for Katanin p60 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Katanin p60

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. [provided by RefSeq]

Long Name

Katanin p60 (ATPase containing) Subunit A 1

Alternate Names

KATNA1

Entrez Gene IDs

11104 (Human)

Gene Symbol

KATNA1

UniProt

O75449 (Human)

Additional Katanin p60 Products

Product Documents for Katanin p60 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Katanin p60 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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