KCNH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84935

Novus Biologicals, part of Bio-Techne
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NBP1-84935
NBP1-84935-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KCNH1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQATVLEVRHELKEDIKALNAKMTNIEKQLSEILRILTSRRSSQSPQELFEISRPQSPES

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCNH1 Antibody

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935] - Analysis in human cerebral cortex and liver tissues. Corresponding KCNH1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935]

Immunohistochemistry-Paraffin: KCNH1 Antibody [NBP1-84935] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.
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Applications for KCNH1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCNH1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Alternate Names

EAG channel 1, EAG1, EAGeag1, Ether-a-go-go potassium channel 1, ether-a-go-go, Drosophila, homolog of, hEAG1, h-eageag, Kv10.1, MGC142269, potassium channel, voltage-gated, subfamily H, member 1, potassium voltage-gated channel subfamily H member 1, potassium voltage-gated channel, subfamily H (eag-related), member 1, Voltage-gated potassium channel subunit Kv10.1

Gene Symbol

KCNH1

Additional KCNH1 Products

Product Documents for KCNH1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KCNH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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