Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Predicted:

Bovine (100%), Guinea Pig (100%), Rabbit (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all KCNK1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1. The immunogen is located within amino acids 220 - 270 of KCNK1. Amino Acid Squence: DYVPGEGYNQKFRELYK

Specificity

KCNK1 antibody is predicted to not cross-react with other KCNK proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KCNK1 Antibody - BSA Free

Western Blot: KCNK1 AntibodyBSA Free [NBP2-41301]

Western Blot: KCNK1 AntibodyBSA Free [NBP2-41301]

Western Blot: KCNK1 Antibody [NBP2-41301] - Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 ug/ml.
KCNK1 Antibody - BSA Free

Immunohistochemistry: KCNK1 Antibody - BSA Free [NBP2-41301] -

Immunohistochemistry: KCNK1 Antibody - BSA Free [NBP2-41301] - Immunohistochemistry of KCNK1 in mouse brain tissue with KCNK1 antibody at 5 u/ml.
KCNK1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: KCNK1 Antibody - BSA Free [NBP2-41301] -

Immunocytochemistry/ Immunofluorescence: KCNK1 Antibody - BSA Free [NBP2-41301] - Immunofluorescence of KCNK1 in mouse brain tissue with KCNK1 antibody at 20 ug/ml.

Applications for KCNK1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCNK1

K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34% homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.

Long Name

Potassium channel subfamily K member 1

Alternate Names

HOHO1, KCNO1, TWIK1

Gene Symbol

KCNK1

Additional KCNK1 Products

Product Documents for KCNK1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KCNK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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