KCNN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-46119

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-46119
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all KCNN2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-ESYDKHVTYNAER corresponding to internal region according to NP_740721.1.

Epitope

Internal region

Specificity

This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for KCNN2 Antibody

Western Blot: KCNN2 Antibody [NBP1-46119]

Western Blot: KCNN2 Antibody [NBP1-46119]

Western Blot: KCNN2 Antibody [NBP1-46119] - Staining of human liver lysate (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119]

Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119]

Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119] - Staining of paraffin embedded human kidney. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119]

Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119]

Immunohistochemistry-Paraffin: KCNN2 Antibody [NBP1-46119] - Staining of paraffin embedded human thyroid gland. Antibody at 3.8 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for KCNN2 Antibody

Application
Recommended Usage

Immunohistochemistry

3.75 ug/mL

Immunohistochemistry-Paraffin

3.75 ug/mL

Peptide ELISA

Detection limit 1:64000

Western Blot

0.3 - 1 ug/mL
Application Notes
WB: Approx. 70 kDa band and 23 kDa band bands observed in human liver lysates (calculated MW of 63.8 kDa band according to NP_067627.2 and of 26.3 kDa band according to NP_740721.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: KCNN2

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Long Name

Small conductance calcium-activated potassium channel protein 2

Alternate Names

KCa2.2, SKCa 2, SKCa2

Entrez Gene IDs

3781 (Human); 140492 (Mouse); 54262 (Rat)

Gene Symbol

KCNN2

UniProt

NP_067627.2 (Human)

Additional KCNN2 Products

Product Documents for KCNN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KCNN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.