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KIR2DL1/KIR2DS5 Antibody (124)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90181

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 124

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human KIR2DL1/KIR2DS5 (Accession#: NP_055033.2; Met1-His245).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for KIR2DL1/KIR2DS5 Antibody (124)

Flow Cytometry: KIR2DL1/KIR2DS5 Antibody (124) [NBP2-90181]

Flow Cytometry: KIR2DL1/KIR2DS5 Antibody (124) [NBP2-90181]

Flow Cytometry: KIR2DL1/KIR2DS5 Antibody (124) [NBP2-90181] - Flow cytometric analysis of Human KIR2DL1(CD158a) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human KIR2DL1(CD158a), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.

Applications for KIR2DL1/KIR2DS5 Antibody (124)

Application
Recommended Usage

Flow Cytometry

1:25-1:100

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KIR2DL1/KIR2DS5

The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.

Alternate Names

CD158a

Gene Symbol

KIR2DL1

Additional KIR2DL1/KIR2DS5 Products

Product Documents for KIR2DL1/KIR2DS5 Antibody (124)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KIR2DL1/KIR2DS5 Antibody (124)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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