Kir3.4 Antibody (8D2)

Novus Biologicals, part of Bio-Techne | Catalog # H00003762-M01-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 8D2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Kir3.4 Antibodies »

Product Specifications

Immunogen

KCNJ5 (NP_000881.3, 321 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Kir3.4 Antibody (8D2)

Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - Detection against Immunogen (36.63 KDa) .
Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

Western Blot: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - KCNJ5 monoclonal antibody (M01), clone 8D2. Western Blot analysis of KCNJ5 expression in K-562.
ELISA: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

ELISA: Kir3.4 Antibody (8D2) [H00003762-M01-100ug]

ELISA: Kir3.4 Antibody (8D2) [H00003762-M01-100ug] - Detection limit for recombinant GST tagged KCNJ5 is 0.03 ng/ml as a capture antibody.

Applications for Kir3.4 Antibody (8D2)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Kir3.4

G-protein regulated inward-rectifier potassium channels (GIRK) are part of a superfamily of inward-rectifier K+ channels. To date four GIRK subunits, designated GIRK1-4 (also designated Kir3.1-4), have been identified in mammals, and GIRK5 has been found in Xenopus oocytes. GIRK channels exist in vivo both as homotetramers and heterotetramers. GIRK channels are modulated by G-proteins; they are also modulated by phosphatidylinositol 4,5-bisphosphate, intracellular sodium, ethanol and mechanical stretch. GIRK1, 2 and 3 are highly abundant in brain. In general, neuronal GIRK channels are involved in the regulation of the excitability of neurons and may contribute to the resting potential.

Alternate Names

Cardiac inward rectifier, CIRKIR3.4, G protein-activated inward rectifier potassium channel 4, GIRK-4, GIRK4Kir3.4, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, inward rectifier K+ channel KIR3.4, IRK-4, KATP-1, KATP1cardiac ATP-sensitive potassium channel, LQT13, Potassium channel, inwardly rectifying subfamily J member 5, potassium inwardly-rectifying channel, subfamily J, member 5

Entrez Gene IDs

3762 (Human)

Gene Symbol

KCNJ5

OMIM

600734 (Human)

UniProt

NP_000881.3 (Human)

Additional Kir3.4 Products

Product Documents for Kir3.4 Antibody (8D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Kir3.4 Antibody (8D2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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