KISS1 Antibody (C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41551

Novus Biologicals, part of Bio-Techne
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NBP3-41551
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C1

Concentration

1 mg/ml

View all Metastin/KiSS1 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human KISS1 (Uniprot#: Q15726; Glu20-Gly138 (Uniprot#: Q15726)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for KISS1 Antibody (C1)

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Metastin/KiSS1

KISS1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KISS1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).

Long Name

KiSS-1 Metastasis-suppressor

Alternate Names

KiSS1, Kisspeptin-1

Gene Symbol

KISS1

Additional Metastin/KiSS1 Products

Product Documents for KISS1 Antibody (C1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KISS1 Antibody (C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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