KISS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45672

Novus Biologicals, part of Bio-Techne
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NBP1-45672-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Metastin/KiSS1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide surrounding amino acid 17 of mouse KiSS-1 (NP_839991).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab286128)

Scientific Data Images for KISS1 Antibody

Western Blot: KISS1 Antibody [NBP1-45672]

Western Blot: KISS1 Antibody [NBP1-45672]

Western Blot: KISS1 Antibody [NBP1-45672] - Analysis of KiSS-1 expression with Jurkat Cell Lysate.

Applications for KISS1 Antibody

Application
Recommended Usage

Western Blot

0.5 - 4 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 5 mM EDTA, 0.5% BSA, 30% Glycerol

Preservative

0.03% Proclin 300

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Metastin/KiSS1

KiSS-1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KiSS-1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).

Long Name

KiSS-1 Metastasis-suppressor

Alternate Names

KiSS1, Kisspeptin-1

Entrez Gene IDs

3814 (Human); 280827 (Mouse)

Gene Symbol

KISS1

UniProt

Q6Y4S4 (Mouse)

Additional Metastin/KiSS1 Products

Product Documents for KISS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KISS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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