Kos1/Tnk1 Antibody [DyLight 550]

Novus Biologicals, part of Bio-Techne | Catalog # NB300-237R

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Kos1/Tnk1 Antibodies »

Product Specifications

Immunogen

C-terminal residues 421-434 [QNQVQSLPAGSAEP] of the 47 kDa mouse Kos1 / Tnk1 protein.

Reactivity Notes

Mouse and human.

Specificity

This is specific for Kos1/Tnk1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Kos1/Tnk1 Antibody [DyLight 550]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Kos1/Tnk1

Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.

Alternate Names

CD38 negative kinase 1;Kinase of embryonic stem cells;MGC46193;non-receptor tyrosine kinase;Non-receptor tyrosine-protein kinase TNK1;TNK1;tyrosine kinase, non-receptor 1;tyrosine kinase, non-receptor, 1

Additional Kos1/Tnk1 Products

Product Documents for Kos1/Tnk1 Antibody [DyLight 550]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Kos1/Tnk1 Antibody [DyLight 550]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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