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Ku70/XRCC6 Antibody (LKAP1-1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27930

Novus Biologicals, part of Bio-Techne
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NBP3-27930

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # LKAP1-1

Concentration

0.2 mg/ml

Product Summary for Ku70/XRCC6 Antibody (LKAP1-1)

Immunogen

A human cell nuclear fraction was used as the immunogen for this Ku70/XRCC6 antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Ku70/XRCC6 Antibody (LKAP1-1)

Application
Recommended Usage

Flow Cytometry

0.5 - 1ug/10e6 cells
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Ku70/XRCC6

The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNAdependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Long Name

Lupus Ku Autoantigen Protein 70

Alternate Names

CTC75, CTCBF, G22P1, ML8, TLAA, XRCC6

Gene Symbol

XRCC6

UniProt

Additional Ku70/XRCC6 Products

Product Documents for Ku70/XRCC6 Antibody (LKAP1-1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Ku70/XRCC6 Antibody (LKAP1-1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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