Laminin gamma 1 Antibody (SR1311)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21953

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21953-100ul
NBP3-21953-50ul
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1311

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Laminin gamma 1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Laminin gamma 1 (Uniprot #: P11047, Q5VYE7, Q6NVY8)

Specificity

Detects endogenous levels of total Laminin gamma 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Laminin gamma 1 Antibody (SR1311)

Western Blot: Laminin gamma 1 Antibody (SR1311) [NBP3-21953] -

Western Blot: Laminin gamma 1 Antibody (SR1311) [NBP3-21953] - Western blot analysis using NBP3-21953 in A431 cell lysate.

Applications for Laminin gamma 1 Antibody (SR1311)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Laminin gamma 1

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.

Alternate Names

LAMC1, Laminin B2

Gene Symbol

LAMC1

Additional Laminin gamma 1 Products

Product Documents for Laminin gamma 1 Antibody (SR1311)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Laminin gamma 1 Antibody (SR1311)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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