LDB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14190

Novus Biologicals, part of Bio-Techne
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NBP2-14190
NBP2-14190-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LDB3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: PIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LDB3 Antibody

Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190]

Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190]

Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry: LDB3 Antibody [NBP2-14190]

Immunohistochemistry: LDB3 Antibody [NBP2-14190]

Immunohistochemistry: LDB3 Antibody [NBP2-14190] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190]

Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190]

Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190] - Staining of human prostate shows low expression as expected.
View 1 more images

Applications for LDB3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LDB3

LDB3 encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]

Alternate Names

CMD1C, CYPHER, KIAA01613, KIAA0613FLJ35865, LDB3Z1, LDB3Z4, LIM domain binding 3, LIM domain-binding protein 3, ORACLE, PDLIM6, PDZ and LIM domain 6, Protein cypher, ZASPLVNC3, Z-band alternatively spliced PDZ-motif protein

Gene Symbol

LDB3

Additional LDB3 Products

Product Documents for LDB3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for LDB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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