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LINGO-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14392

Novus Biologicals, part of Bio-Techne
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NBP3-14392

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Avian (100%), Bat (94%), Bovine (100%), Chicken (100%), Equine (94%), Monkey (100%), Mouse (100%), Opossum (100%), Orangutan (100%), Porcine (100%), Primate (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from C-Terminus of human LINGO-1.

Epitope

C-Terminus

Reactivity Notes

Expected reactivity based on percent sequence identity: Canine (88%), Rabbit (81%)

Specificity

Human LINGO-1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for LINGO-1 Antibody

Immunohistochemistry-Paraffin: LINGO-1 Antibody [NBP3-14392]

Immunohistochemistry-Paraffin: LINGO-1 Antibody [NBP3-14392]

Immunohistochemistry-Paraffin: LINGO-1 Antibody [NBP3-14392] - Immunohistochemistry of formalin-fixed, paraffin-embedded human hippocampus after heat-induced antigen retrieval.

Applications for LINGO-1 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: LINGO-1

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible forsome inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator ofoligodentrocyte differentiation and axonal myelination

Long Name

Leucine-rich Repeat And Ig Domain Containing Nogo Receptor-Interacting Protein 1

Alternate Names

LERN1, LINGO1, LRRN6A

Gene Symbol

LINGO1

Additional LINGO-1 Products

Product Documents for LINGO-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LINGO-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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