Lipid A LPS Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64484

Novus Biologicals, part of Bio-Techne
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NB100-64484
NB100-64484-0.1ml
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Key Product Details

Species Reactivity

Bacteria

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Format

BSA Free

Concentration

4 mg/ml

View all Lipid A LPS Antibodies »

Product Specifications

Immunogen

Whole cell preparation of lipid A from E. coli O157

Specificity

NB100-64484 recognizes the Lipid A or endotoxin region of LPS (Lipopolysaccharide) from E. coli. Lipid A is a glucosamine-based phospholipid which forms part of the bacterial outer membrane and anchors LPS to the surface of the bacteria. This antibody cross reacts with P. aeruginosa, K. pneumoniae, S. enteriditis, E. aerogenes, E. hermanii, Y. enterocolitica and S. sonnei.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Lipid A LPS Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Lipid A LPS Antibody - BSA Free [NB100-64484]

Immunocytochemistry/ Immunofluorescence: Lipid A LPS Antibody - BSA Free [NB100-64484]

Immunocytochemistry/Immunofluorescence: Lipid A LPS Antibody [NB100-64484] - IF assay using NB100-64484 at a 1:100 dilution to stain Shigella Sonnei using above protocol. The magnification is 400X.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

4 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lipid A LPS

Lipid A is a lipid component of an endotoxin held responsible for toxicity of Gram-negative bacteria. Sensing of lipid A by the human immune system may also be critical for the onset of immune responses to Gram-negative infection, and for the subsequent successful fight against the infection. Lipid A is located at one end of the lipopolysaccharide (LPS, also called endotoxin) molecule, and anchors the LPS to the outer membrane of a Gram-negative bacteria. Many of the immune activating abilities of LPS can be contributed to the lipid A unit. It is a very potent stimulant of the immune system, activating cells (for example, monocytes or macrophages) at picogram per milliliter quantities. When present in the body at high concentrations during a Gram-negative bacterial infection, it may cause shock and death by an "out of control" excessive immune reaction.

Alternate Names

Lipid A Lipopolysaccharide

Additional Lipid A LPS Products

Product Documents for Lipid A LPS Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Lipid A LPS Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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