Liprin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38494

Novus Biologicals, part of Bio-Techne
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NBP2-38494
NBP2-38494-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Liprin alpha 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QLEETQHDKDQLVLNIEALRAELDHMRLRGASLHHGRPHLGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDADVSDGEDDRDTLLSSVDLLS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Liprin alpha 1 Antibody

Immunocytochemistry/ Immunofluorescence: Liprin alpha 1 Antibody [NBP2-38494]

Immunocytochemistry/ Immunofluorescence: Liprin alpha 1 Antibody [NBP2-38494]

Immunocytochemistry/Immunofluorescence: Liprin alpha 1 Antibody [NBP2-38494] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & focal adhesion sites.
Immunohistochemistry-Paraffin: Liprin alpha 1 Antibody [NBP2-38494]

Immunohistochemistry-Paraffin: Liprin alpha 1 Antibody [NBP2-38494]

Immunohistochemistry-Paraffin: Liprin alpha 1 Antibody [NBP2-38494] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Applications for Liprin alpha 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Liprin alpha 1

Liprin alpha 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.

Alternate Names

FLJ42630, FLJ43474, LAR-interacting protein 1, LIP.1, LIP-1, LIP1FLJ41337, LIPRIN, Liprin-alpha1, liprin-alpha-1, MGC26800, Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1, PTPRF-interacting protein alpha-1

Gene Symbol

PPFIA1

UniProt

Q13136 (Human)

Additional Liprin alpha 1 Products

Product Documents for Liprin alpha 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Liprin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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