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LNK/SH2B3 Antibody (OTI2D8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-00641

Novus Biologicals, part of Bio-Techne
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NBP2-00641
Conjugate
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2D8

Concentration

0.37 mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LNK/SH2B3 Antibody (OTI2D8)

Western Blot: LNK/SH2B3 Antibody (OTI2D8) [NBP2-00641]

Western Blot: LNK/SH2B3 Antibody (OTI2D8) [NBP2-00641]

Western Blot: LNK Antibody (2D8) [NBP2-00641] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LNK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LNK.
Immunocytochemistry/Immunofluorescence: LNK Antibody (2D8) [NBP2-00641] Staining of COS7 cells transiently transfected by pCMV6-ENTRY LNK.
Immunohistochemistry-Paraffin: LNK/SH2B3 Antibody (OTI2D8) [NBP2-00641]

Immunohistochemistry-Paraffin: LNK/SH2B3 Antibody (OTI2D8) [NBP2-00641]

Immunohistochemistry-Paraffin: LNK Antibody (2D8) [NBP2-00641] - Staining of paraffin-embedded Human pancreas tissue using anti-LNK mouse monoclonal antibody.

Applications for LNK/SH2B3 Antibody (OTI2D8)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.37 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LNK/SH2B3

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Long Name

Lymphocyte Adapter Protein

Alternate Names

SH2B3

Entrez Gene IDs

10019 (Human)

Gene Symbol

SH2B3

Additional LNK/SH2B3 Products

Product Documents for LNK/SH2B3 Antibody (OTI2D8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LNK/SH2B3 Antibody (OTI2D8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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