LRP-1 Antibody (8G1) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NB600-1477
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # 8G1
Format
Azide and BSA Free
Concentration
2.1 mg/ml
Product Specifications
Immunogen
Human LRP/alpha2 MR
Localization
Type I membrane protein.
Specificity
Specifically reacts with the 515kDa alpha-chain of human LRP/alpha2 MR expressed in certain cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in the CNS, fibroblasts, smooth muscle cells and monocyte-derived foam cells in atherosclerotic lesions of arterial walls. Will block a2M binding.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for LRP-1 Antibody (8G1) - Azide and BSA Free
Application
Recommended Usage
Flow Cytometry
1:10-1:1000
Immunohistochemistry
1-10 ug/ml
Immunohistochemistry-Frozen
1-10 ug/ml
Immunohistochemistry-Paraffin
1-10 ug/ml
Western Blot
1-5 ug/ml
Application Notes
Specifically reacts with the 515 kDa alpha-chain of human LRP/alpha2 MR expressed in certain cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in the CNS, fibroblasts, smooth muscle cells and monocyte-derived foam cells in atherosclerotic lesions of arterial walls. Will block a2M binding. Flow cytometry will recognize an epitope on the extracellular domain.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
50mM Sodium Phosphate (pH 7.4) and 0.15M NaCl
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
2.1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -70C. Avoid freeze-thaw cycles.
Background: LRP-1
Long Name
LDL Receptor-related Protein 1
Alternate Names
A2MR, Alpha-2-Macroglobulin Receptor, APOER, Apolipoprotein E receptor, APR, CD91, CD91 antigen, EC 1.1.1.94, EC 3.4.21.9, IGFBP3R, low density lipoprotein receptor-related protein 1, LRP, LRP-1, LRP1A, prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor
Entrez Gene IDs
4035 (Human)
Gene Symbol
LRP1
Additional LRP-1 Products
Product Documents for LRP-1 Antibody (8G1) - Azide and BSA Free
Product Specific Notices for LRP-1 Antibody (8G1) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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