LSD1 Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76688F

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-76688AF350

Alexa Fluor 405

NBP1-76688AF405

Alexa Fluor 488

NBP1-76688AF488

Alexa Fluor 532

NBP1-76688AF532

Alexa Fluor 594

NBP1-76688AF594

Alexa Fluor 647

NBP1-76688AF647

Alexa Fluor 700

NBP1-76688AF700

Alexa Fluor 750

NBP1-76688AF750

Biotin

NBP1-76688B

CoraFluor 1

NBP1-76688CL1

DyLight 350

NBP1-76688UV

DyLight 405

NBP1-76688V

DyLight 488

NBP1-76688G

DyLight 550

NBP1-76688R

DyLight 594

NBP1-76688DL594

DyLight 650

NBP1-76688C

DyLight 680

NBP1-76688FR

DyLight 755

NBP1-76688IR

HRP

NBP1-76688H

Janelia Fluor 525

NBP1-76688JF525

Janelia Fluor 549

NBP1-76688JF549

Janelia Fluor 646

NBP1-76688JF646

Janelia Fluor 669

NBP1-76688JF669

mFluor Violet 450 SE

NBP1-76688MFV450

mFluor Violet 500 SE

NBP1-76688MFV500

mFluor Violet 610 SE

NBP1-76688MFV610

PerCP

NBP1-76688PCP

Forumulation

Catalog #

BSA Free

NBP1-76688

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lysine (K)-specific Demethylase 1A/KDM1A/LSD1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the center of human LSD1. The immunogen is located within amino acids 140 - 190 of LSD1. Amino Acid Squence: QAPPEEENESEPEEPS

Reactivity Notes

0

Marker

Nucleus Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for LSD1 Antibody [FITC]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Lysine (K)-specific Demethylase 1A/KDM1A/LSD1

LSD1 a recently identified, first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys-4 of histone H3, a specific tag for epigenetic transcriptional activation. Reports suggest that it plays an important role in stimulating androgen-receptor-dependent transcription converting oxygen to hydrogen peroxide (might use alternative electron acceptors). Along with nuclear FHL2 it serves as a novel biomarker predictive for prostate cancer.

Alternate Names

AOF2, BHC110, LSD1, Lysine (K)specific Demethylase 1A

Gene Symbol

KDM1A

Additional Lysine (K)-specific Demethylase 1A/KDM1A/LSD1 Products

Product Documents for LSD1 Antibody [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for LSD1 Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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