Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # LST1/02

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LST1 Antibodies »

Product Specifications

Immunogen

KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1

Specificity

The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for LST1 Antibody (LST1/02) [DyLight 755]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: LST1

LST1, also known as Leukocyte-specific transcript 1 protein, has 10 isoforms ranging from a 13 amino acid isoform that is 1 kDa to a 97 amino acid isoform that is 11 kDa, can inhibit the proliferation of lymphocytes, induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may participate in dendritic cell maturation. Disease research is currently being performed with relation to LST1 and vulvovaginitis, rhinotracheitis, chronic venous leg ulcers, proliferative vitreoretinopathy, systemic lupus erythematosus, vitreoretinopathy, rubella, lupus erythematosus, tonsillitis, diabetes mellitus, lung cancer, and Graves' disease. Interactions with this protein have been shown to involve G2E3, PRKCB and CACTIN in cell morphogenesis, immune response, regulation of cell shape, anatomical structure morphogenesis, and dendrite development pathways.

Alternate Names

B144D6S49ELST-1, leucocyte specific transcript 1, leukocyte specific transcript 1, leukocyte-specific transcript 1 protein, lymphocyte antigen 117, MGC119006, MGC119007, Protein B144

Gene Symbol

LST1

Additional LST1 Products

Product Documents for LST1 Antibody (LST1/02) [DyLight 755]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LST1 Antibody (LST1/02) [DyLight 755]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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