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LXR beta/NR1H2 Antibody (2H2-H3)

Novus Biologicals, part of Bio-Techne | Catalog # H00007376-M01

Novus Biologicals, part of Bio-Techne
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H00007376-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2H2-H3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

NR1H2 (AAH07790.1, 1 a.a. ~ 461 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Localization

Nuclear

Specificity

NR1H2 - nuclear receptor subfamily 1, group H, member 2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for LXR beta/NR1H2 Antibody (2H2-H3)

Western Blot: LXR beta/NR1H2 Antibody (2H2-H3) [H00007376-M01]

Western Blot: LXR beta/NR1H2 Antibody (2H2-H3) [H00007376-M01]

Western Blot: LXR beta/NR1H2 Antibody (2H2-H3) [H00007376-M01] - NR1H2 monoclonal antibody (M01), clone 2H2-H3 Analysis of NR1H2 expression in LNCaP.
Sandwich ELISA: LXR beta/NR1H2 Antibody (2H2-H3) [H00007376-M01] - Detection limit for recombinant GST tagged NR1H2 is approximately 0.3ng/ml as a capture antibody.

Applications for LXR beta/NR1H2 Antibody (2H2-H3)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LXR beta/NR1H2

The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM]

Long Name

Liver X Receptor beta

Alternate Names

NER-I, NR1H2, RIP15, UNR

Entrez Gene IDs

7376 (Human)

Gene Symbol

NR1H2

OMIM

600380 (Human)

Additional LXR beta/NR1H2 Products

Product Documents for LXR beta/NR1H2 Antibody (2H2-H3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LXR beta/NR1H2 Antibody (2H2-H3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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