LXR beta/NR1H2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1464

Novus Biologicals, part of Bio-Techne
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NB100-1464
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all LXR beta/NR1H2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence SSPTTSSLDTPLPGC corresponding to N-Terminus according to NP_009052.3.

Specificity

Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for LXR beta/NR1H2 Antibody

Immunocytochemistry/ Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-1464]

Immunocytochemistry/ Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-1464]

Immunocytochemistry/Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-1464] - Analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).
Flow Cytometry: LXR beta/NR1H2 Antibody [NB100-1464]

Flow Cytometry: LXR beta/NR1H2 Antibody [NB100-1464]

Flow Cytometry: LXR beta/NR1H2 Antibody [NB100-1464] - Analysis of paraformaldehyde fixed HeLa cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Applications for LXR beta/NR1H2 Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/mL

Immunocytochemistry/ Immunofluorescence

10 ug/mL

Peptide ELISA

Detection limit 1:28000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LXR beta/NR1H2

Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver, whereas the beta isoform expression has been shown to be ubiquitous.

Long Name

Liver X Receptor beta

Alternate Names

NER-I, NR1H2, RIP15, UNR

Entrez Gene IDs

7376 (Human)

Gene Symbol

NR1H2

UniProt

P55055 (Human)

Additional LXR beta/NR1H2 Products

Product Documents for LXR beta/NR1H2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for LXR beta/NR1H2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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