LXR beta/NR1H2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-74457

Novus Biologicals, part of Bio-Techne
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NB100-74457
NB100-74457-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all LXR beta/NR1H2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta.

Localization

Nuclear

Specificity

Detects LXR beta in rat and mouse samples.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LXR beta/NR1H2 Antibody

Western Blot: LXR beta/NR1H2 Antibody [NB100-74457]

Western Blot: LXR beta/NR1H2 Antibody [NB100-74457]

Western Blot: LXR beta/NR1H2 Antibody [NB100-74457] - 25 ug of rat liver (Lane 1), mouse liver (Lane 2) and Hela (Lane 3) cell lysates.
Immunocytochemistry/ Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-74457]

Immunocytochemistry/ Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-74457]

Immunocytochemistry/Immunofluorescence: LXR beta/NR1H2 Antibody [NB100-74457] - Analysis of LXR beta (green) showing positive staining in the nuclear envelope of C2C12 cells (right) compared with a negative control in the absence of primary antibody (left).

Applications for LXR beta/NR1H2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:200 - 1:1000

Western Blot

1:200 - 1:2000
Application Notes
WB: Detects an approx. 51 kDa protein representing LXR beta in rat and mouse liver samples.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LXR beta/NR1H2

Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous. The corresponding gene for the LXR beta is NR1H2.

Long Name

Liver X Receptor beta

Alternate Names

NER-I, NR1H2, RIP15, UNR

Entrez Gene IDs

7376 (Human); 22260 (Mouse); 58851 (Rat)

Gene Symbol

NR1H2

UniProt

P55055 (Human)

Additional LXR beta/NR1H2 Products

Product Documents for LXR beta/NR1H2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for LXR beta/NR1H2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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