Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor® 488]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80054AF488
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Mouse
Applications
Flow Cytometry, Functional Assay
Label
Alexa Fluor 488 (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 4H8 WH2
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor® 488]
Immunogen
Recombinant mouse Lymphotoxin beta R/TNFRSF3 (cysteine-rich region/aa 31-221).
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor® 488]
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional Assay
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
The monoclonal antibody to mouse LT-beta-R is an agonist that can be used for the investigation of the regulation of BAFF (BlyS), chemokines and integrins using in vivo and tissue culture models, the development of NK cells and NK T cells, to study the regulation of NF-kappa-B family of transcription factors in regulation of inflammation and homeostasis, particularly RelB NF-kappa-B2 pathway. For use as an agonist the MAb to LT-beta-R is added to cell cultures at 2ug/ml. For in vivo use, mice are injected intraperitoneally with 50ug of agonistic MAb to LT-beta-R in sterile phosphate saline buffer. Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
>95%, by SDS-PAGE
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Lymphotoxin beta R/TNFRSF3
Long Name
Lymphotoxin beta Receptor
Alternate Names
LTBR, LymphotoxinbR, TNF RIII, TNF Rrp, TNFRSF3
Gene Symbol
LTBR
Additional Lymphotoxin beta R/TNFRSF3 Products
Product Documents for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor® 488]
Product Specific Notices for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Alexa Fluor® 488]
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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