Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Janelia Fluor® 549]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80054JF549
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Label
Janelia Fluor 549
Antibody Source
Monoclonal Rat IgG2A Clone # 4H8 WH2
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant mouse Lymphotoxin beta R/TNFRSF3 (cysteine-rich region/aa 31-221).
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Janelia Fluor® 549]
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional Assay
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
The monoclonal antibody to mouse LT-beta-R is an agonist that can be used for the investigation of the regulation of BAFF (BlyS), chemokines and integrins using in vivo and tissue culture models, the development of NK cells and NK T cells, to study the regulation of NF-kappa-B family of transcription factors in regulation of inflammation and homeostasis, particularly RelB NF-kappa-B2 pathway. For use as an agonist the MAb to LT-beta-R is added to cell cultures at 2ug/ml. For in vivo use, mice are injected intraperitoneally with 50ug of agonistic MAb to LT-beta-R in sterile phosphate saline buffer. Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
>95%, by SDS-PAGE
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Lymphotoxin beta R/TNFRSF3
Long Name
Lymphotoxin beta Receptor
Alternate Names
LTBR, LymphotoxinbR, TNF RIII, TNF Rrp, TNFRSF3
Gene Symbol
LTBR
Additional Lymphotoxin beta R/TNFRSF3 Products
Product Specific Notices for Lymphotoxin beta R/TNFRSF3 Antibody (4H8 WH2) [Janelia Fluor® 549]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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