Lyn [p Tyr397] Antibody (HL122)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13673

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-13673
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL122

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lyn Antibodies »

Product Summary for Lyn [p Tyr397] Antibody (HL122)

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Tyr397 of human Lyn. The exact sequence is proprietary.

Modification

p Tyr 397

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for Lyn [p Tyr397] Antibody (HL122)

Western Blot: Lyn [p Tyr397] Antibody (HL122) [NBP3-13673] - Untreated (-) and treated (+) Raji whole cell extract (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Lyn (phospho Tyr397) antibody (NBP3-13673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Lyn [p Tyr397] Antibody (HL122)

Immunohistochemistry-Paraffin: Lyn [p Tyr397] Antibody (HL122) [NBP3-13673] -

Immunohistochemistry-Paraffin: Lyn [p Tyr397] Antibody (HL122) [NBP3-13673] - Lyn antibody [HL122] detects Lyn protein in the occipital lobe of human Alzheimer's disease brain by immunohistochemical analysis.
Sample: Paraffin-embedded Human Matched Pair Tissue Array - Brain (Alzheimer's Disease + Normal) .
Lyn stained by Lyn antibody [HL122] (NBP3-13673) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Lyn [p Tyr397] Antibody (HL122)

Immunohistochemistry-Paraffin: Lyn [p Tyr397] Antibody (HL122) [NBP3-13673] -

Immunohistochemistry-Paraffin: Lyn [p Tyr397] Antibody (HL122) [NBP3-13673] - Lyn antibody detects Lyn protein by immunohistochemical analysis.
Sample: Paraffin-embedded mouse tissues.
Lyn stained by Lyn antibody (NBP3-13673) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for Lyn [p Tyr397] Antibody (HL122)

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lyn

Src is the human homolog of the v-Src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family kinases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src-family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. The human Lyn gene maps to chromosome 8q13 and encodes a 505 amino acid protein. Hematopoietic tissues predominantly express Lyn, which influences normal immunoglobulin production and regulation.

Long Name

V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog

Alternate Names

Hck-2, JTK8, v-yes-1

Gene Symbol

LYN

Additional Lyn Products

Product Documents for Lyn [p Tyr397] Antibody (HL122)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Lyn [p Tyr397] Antibody (HL122)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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