Lyp/PTPN22 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81277

Novus Biologicals, part of Bio-Techne
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NBP1-81277
NBP1-81277-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lyp Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SEISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPITRTKS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lyp/PTPN22 Antibody

Immunohistochemistry-Paraffin: Lyp/PTPN22 Antibody [NBP1-81277]

Immunohistochemistry-Paraffin: Lyp/PTPN22 Antibody [NBP1-81277]

Immunohistochemistry-Paraffin: Lyp/PTPN22 Antibody [NBP1-81277] - Staining of human lymph node shows stark cytoplasmic positivity in a subset of germinal center cells and non-germinal center cells.

Applications for Lyp/PTPN22 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lyp

PTPN22 encodes a protein tyrosine phosphatase which is expressed primarily in lymphoid tissues. This enzyme associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Long Name

Lymphoid Phosphatase

Alternate Names

LyPTP, PEP, PTPN22, PTPN8 (former)

Gene Symbol

PTPN22

Additional Lyp Products

Product Documents for Lyp/PTPN22 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lyp/PTPN22 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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