Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-47815

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI5B9

Concentration

1 mg/ml

View all Lysine (K)-specific Demethylase 4C/KDM4C Antibodies »

Product Summary for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

Immunogen

Full-length protein expressed in 293T cell transfected with human KDM4C expression vector

Specificity

This antibody is specific for Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

Western Blot: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Western Blot: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Western Blot: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JMJD2C(Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-JMJD2C.
Immunocytochemistry/ Immunofluorescence: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Immunocytochemistry/ Immunofluorescence: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Immunocytochemistry/Immunofluorescence: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY JMJD2C.
Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815]

Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9) [NBP1-47815] - Staining of paraffin-embedded pancreas tissue using anti-JMJD2C mouse monoclonal antibody.
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Applications for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Lysine (K)-specific Demethylase 4C/KDM4C

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Alternate Names

GASC1, JHDM3C, JMJD2C, KDM4C, Lysine (K)specific Demethylase 4C

Entrez Gene IDs

23081 (Human)

Gene Symbol

KDM4C

Additional Lysine (K)-specific Demethylase 4C/KDM4C Products

Product Documents for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody (OTI5B9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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