Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI8B2

Concentration

1 mg/ml

View all Lysyl Oxidase Homolog 2/LOXL2 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 152-450 of human LOXL2(NP_002309) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2)

Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2) [NBP2-45669]

Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2) [NBP2-45669]

Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (8B2) [NBP2-45669] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)
Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2) [NBP2-45669]

Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2) [NBP2-45669]

Immunohistochemistry-Paraffin: Lysyl Oxidase Homolog 2/LOXL2 Antibody (8B2) [NBP2-45669] - Analysis of Human endometrium tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)

Applications for Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2)

Application
Recommended Usage

Immunohistochemistry

1:150

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Lysyl Oxidase Homolog 2/LOXL2

LOXL2 encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]

Alternate Names

LOL2, LOXL2

Gene Symbol

LOXL2

Additional Lysyl Oxidase Homolog 2/LOXL2 Products

Product Documents for Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Lysyl Oxidase Homolog 2/LOXL2 Antibody (OTI8B2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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