MAGED2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24694

Novus Biologicals, part of Bio-Techne
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NBP2-24694
NBP2-24694SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine, Equine, Primate

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MAGED2 Antibodies »

Product Specifications

Immunogen

human MAGE-D2 was used as the immunogen.

Reactivity Notes

Chimpanzee

Specificity

This antibody may also recognize Maged1 as one of the Maged2 sequences used for immunogen is 94% homologous to Maged1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAGED2 Antibody

Western Blot: MAGED2 Antibody [NBP2-24694]

Western Blot: MAGED2 Antibody [NBP2-24694]

Western Blot: MAGED2 Antibody [NBP2-24694] - Analysis of MAGE-D1/2 in A375 cell lysate using NBP2-24694 at 5 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and Picotect ECL substrate solution were used for this test.

Applications for MAGED2 Antibody

Application
Recommended Usage

Western Blot

5-7 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAGED2

MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.

Alternate Names

11B6MAGE-D2 antigen, BCG-1, BCG1MAGEDHCA10, breast cancer associated gene 1, Breast cancer-associated gene 1 protein, hepatocellular carcinoma associated protein, hepatocellular carcinoma-associated protein HCA10, Hepatocellular carcinoma-associated protein JCL-1, JCL-1, MAGE-D2, melanoma antigen family D, 2, melanoma-associated antigen D2, MGC8386

Gene Symbol

MAGED2

Additional MAGED2 Products

Product Documents for MAGED2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MAGED2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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