MANBA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47384

Novus Biologicals, part of Bio-Techne
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NBP2-47384
NBP2-47384-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MANBA/Beta-Mannosidase Antibodies »

Product Summary for MANBA Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MANBA Antibody

Immunocytochemistry/ Immunofluorescence: MANBA Antibody [NBP2-47384]

Immunocytochemistry/ Immunofluorescence: MANBA Antibody [NBP2-47384]

Immunocytochemistry/Immunofluorescence: MANBA Antibody [NBP2-47384] - Staining human cell line A549 shows positivity in vesicles. Antibody staining is shown i green.
Immunohistochemistry-Paraffin: MANBA Antibody [NBP2-47384]

Immunohistochemistry-Paraffin: MANBA Antibody [NBP2-47384]

Immunohistochemistry-Paraffin: MANBA Antibody [NBP2-47384] - Staining of human prostate shows strong cytoplasmic positivity, with a granular pattern in glandular cells.

Applications for MANBA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MANBA/Beta-Mannosidase

MANBA encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.

Long Name

Beta-Mannosidase

Alternate Names

MANB1, Mannanase, Mannase

Gene Symbol

MANBA

Additional MANBA/Beta-Mannosidase Products

Product Documents for MANBA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MANBA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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