MAPKAP Kinase 3 Antibody (SR1737)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22593

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22593-100ul
NBP3-22593-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1737

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAPKAP Kinase 3 Antibodies »

Product Summary for MAPKAP Kinase 3 Antibody (SR1737)

Immunogen

A synthesized peptide derived from human MAPKAP Kinase 3 (Uniprot #: Q16644)

Specificity

Detects endogenous levels of total MAPKAP Kinase 3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MAPKAP Kinase 3 Antibody (SR1737)

Western Blot: MAPKAP Kinase 3 Antibody (SR1737) [NBP3-22593] -

Western Blot: MAPKAP Kinase 3 Antibody (SR1737) [NBP3-22593] - Western blot analysis using NBP3-22593 in Jurkat cell lysate.

Applications for MAPKAP Kinase 3 Antibody (SR1737)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAPKAP Kinase 3

MAPKAP Kinase 3 encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.

Alternate Names

3PKEC 2.7.11.1, Chromosome 3p kinase, EC 2.7.11, MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP33pK, MAPKAPK-3, mitogen-activated protein kinase-activated protein kinase 3

Gene Symbol

MAPKAPK3

Additional MAPKAP Kinase 3 Products

Product Documents for MAPKAP Kinase 3 Antibody (SR1737)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MAPKAP Kinase 3 Antibody (SR1737)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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