MAPKAP Kinase 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58080

Novus Biologicals, part of Bio-Techne
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NBP2-58080
NBP2-58080-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MAPKAP Kinase 3 Antibodies »

Product Summary for MAPKAP Kinase 3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAPKAP Kinase 3 Antibody

Western Blot: MAPKAP Kinase 3 Antibody [NBP2-58080]

Western Blot: MAPKAP Kinase 3 Antibody [NBP2-58080]

Western Blot: MAPKAP Kinase 3 Antibody [NBP2-58080] - Analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: MAPKAP Kinase 3 Antibody [NBP2-58080]

Immunocytochemistry/ Immunofluorescence: MAPKAP Kinase 3 Antibody [NBP2-58080]

Immunocytochemistry/Immunofluorescence: MAPKAP Kinase 3 Antibody [NBP2-58080] - Staining of human cell line PC-3 shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for MAPKAP Kinase 3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAPKAP Kinase 3

MAPKAP Kinase 3 encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.

Alternate Names

3PKEC 2.7.11.1, Chromosome 3p kinase, EC 2.7.11, MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP33pK, MAPKAPK-3, mitogen-activated protein kinase-activated protein kinase 3

Gene Symbol

MAPKAPK3

Additional MAPKAP Kinase 3 Products

Product Documents for MAPKAP Kinase 3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MAPKAP Kinase 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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