Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Matrilin-1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human MATN1. The immunogen is located within amino acids 120 - 170 of MATN1. Amino Acid Squence: EGGRSRSPDISK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Matrilin-1 Antibody - BSA Free

Western Blot: Matrilin-1 AntibodyBSA Free [NBP1-76325]

Western Blot: Matrilin-1 AntibodyBSA Free [NBP1-76325]

Western Blot: Matrilin-1 Antibody [NBP1-76325] - Mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.

Applications for Matrilin-1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Matrilin-1

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Alternate Names

CMP, CRTM, MATN1, Matrilin1

Gene Symbol

MATN1

UniProt

NP_002370 (Human)

Additional Matrilin-1 Products

Product Documents for Matrilin-1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Matrilin-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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