MAVS Antibody (58N3E1) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22378F

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-22378

Alexa Fluor 350

NBP2-22378AF350

Alexa Fluor 405

NBP2-22378AF405

Alexa Fluor 488

NBP2-22378AF488

Alexa Fluor 532

NBP2-22378AF532

Alexa Fluor 594

NBP2-22378AF594

Alexa Fluor 647

NBP2-22378AF647

Alexa Fluor 700

NBP2-22378AF700

Alexa Fluor 750

NBP2-22378AF750

Biotin

NBP2-22378B

CoraFluor 1

NBP2-22378CL1

DyLight 350

NBP2-22378UV

DyLight 405

NBP2-22378V

DyLight 488

NBP2-22378G

DyLight 550

NBP2-22378R

DyLight 594

NBP2-22378DL594

DyLight 650

NBP2-22378C

DyLight 680

NBP2-22378FR

DyLight 755

NBP2-22378IR

HRP

NBP2-22378H

Janelia Fluor 525

NBP2-22378JF525

Janelia Fluor 549

NBP2-22378JF549

Janelia Fluor 585

NBP2-22378JF585

Janelia Fluor 635

NBP2-22378JF635

Janelia Fluor 646

NBP2-22378JF646

Janelia Fluor 669

NBP2-22378JF669

mFluor Violet 450 SE

NBP2-22378MFV450

mFluor Violet 500 SE

NBP2-22378MFV500

mFluor Violet 610 SE

NBP2-22378MFV610

Forumulation

Catalog #

Azide and BSA Free

NBP2-80840

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 58N3E1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAVS Antibodies »

Product Summary for MAVS Antibody (58N3E1) [FITC]

Immunogen

Within the range of amino acids 93-298 of human MAVS (isoform 1) were used as the immunogen for this antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for MAVS Antibody (58N3E1) [FITC]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MAVS

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).[supplied by OMIM]

Long Name

Mitochondrial Antiviral Signaling Protein

Alternate Names

Cardif, IPS-1, VISA

Gene Symbol

MAVS

Additional MAVS Products

Product Documents for MAVS Antibody (58N3E1) [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MAVS Antibody (58N3E1) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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