MAVS Antibody (OTI9C4) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72593B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-45757

Alexa Fluor 350

NBP2-72593AF350

Alexa Fluor 405

NBP2-72593AF405

Alexa Fluor 488

NBP2-72593AF488

Alexa Fluor 532

NBP2-72593AF532

Alexa Fluor 594

NBP2-72593AF594

Alexa Fluor 647

NBP2-72593AF647

Alexa Fluor 700

NBP2-72593AF700

Alexa Fluor 750

NBP2-72593AF750

Allophycocyanin

NBP2-72593APC

CoraFluor 1

NBP2-72593CL1

DyLight 350

NBP2-72593UV

DyLight 405

NBP2-72593V

DyLight 488

NBP2-72593G

DyLight 550

NBP2-72593R

DyLight 594

NBP2-72593DL594

DyLight 650

NBP2-72593C

DyLight 680

NBP2-72593FR

DyLight 755

NBP2-72593IR

FITC

NBP2-72593F

HRP

NBP2-72593H

Janelia Fluor 525

NBP2-72593JF525

Janelia Fluor 549

NBP2-72593JF549

Janelia Fluor 585

NBP2-72593JF585

Janelia Fluor 635

NBP2-72593JF635

Janelia Fluor 646

NBP2-72593JF646

Janelia Fluor 669

NBP2-72593JF669

PE

NBP2-72593PE

PerCP

NBP2-72593PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-72593

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ Clone # OTI9C4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAVS Antibodies »

Product Specifications

Immunogen

Recombinant protein fragment corresponding to amino acids 1-247 of human MAVS (NP_065797) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for MAVS Antibody (OTI9C4) [Biotin]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MAVS

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).[supplied by OMIM]

Long Name

Mitochondrial Antiviral Signaling Protein

Alternate Names

Cardif, IPS-1, VISA

Gene Symbol

MAVS

Additional MAVS Products

Product Documents for MAVS Antibody (OTI9C4) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MAVS Antibody (OTI9C4) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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