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MCF2L Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33422

Novus Biologicals, part of Bio-Techne
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NBP1-33422

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human MCF2L. The exact sequence is proprietary.

Reactivity Notes

Rat (89%).

Localization

Cytoplasm, Cell membrane, Peripheral membrane protein, Cytoplasmic side

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

128 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MCF2L Antibody

Western Blot: MCF2L Antibody [NBP1-33422]

Western Blot: MCF2L Antibody [NBP1-33422]

Western Blot: MCF2L Antibody [NBP1-33422] - Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 5% SDS PAGE; antibody diluted at 1:1000.

Applications for MCF2L Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MCF2L

Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus . Isoform 5 activates CDC42

Alternate Names

DBL's big sister, DBS, FLJ12122, guanine nucleotide exchange factor DBS, KIAA0362ARHGEF14, MCF.2 cell line derived transforming sequence-like, MCF2 transforming sequence-like protein, MCF2-transforming sequence-like protein, OST

Gene Symbol

MCF2L

Additional MCF2L Products

Product Documents for MCF2L Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MCF2L Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.