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Mcl-1 Antibody (HL1544) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25560

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-25560

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human, Mouse, Rat, Canine, Feline

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL1544

Format

Azide and BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Mcl-1. The exact sequence is proprietary.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mcl-1 Antibody (HL1544) - Azide and BSA Free

Mcl-1 Antibody (HL1544) - Azide and BSA Free

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] -

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] - MCL1 antibody [HL1544] detects MCL1 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. MCL1 stained by MCL1 antibody [HL1544] (NBP3-25560) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Mcl-1 Antibody (HL1544) - Azide and BSA Free

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] -

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] - MCL1 antibody [HL1544] detects MCL1 protein by immunohistochemical analysis. Sample: Paraffin-embedded cat tissue. MCL1 stained by MCL1 antibody [HL1544] (NBP3-25560) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Mcl-1 Antibody (HL1544) - Azide and BSA Free

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] -

Immunohistochemistry-Paraffin: Mcl-1 Antibody (HL1544) - Azide and BSA Free [NBP3-25560] - MCL1 antibody [HL1544] detects MCL1 protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse tissues. MCL1 stained by MCL1 antibody [HL1544] (NBP3-25560) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for Mcl-1 Antibody (HL1544) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mcl-1

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Long Name

Myeloid Cell Leukemia Sequence 1

Alternate Names

BCL2L3, Mcl1

Gene Symbol

MCL1

Additional Mcl-1 Products

Product Documents for Mcl-1 Antibody (HL1544) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mcl-1 Antibody (HL1544) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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