Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all MCM6 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 775 and the C-terminus (residue 821) of human Minichromosome Maintenance 6 using the numbering given in entry NP_005906.2 (GeneID 4175).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCM6 Antibody

Western Blot: MCM6 Antibody [NB100-291]

Western Blot: MCM6 Antibody [NB100-291]

Western Blot: MCM6 Antibody [NB100-291] - RIPA extract (50 ug) from HeLa cells. Antibody used at 0.2 ug/ml.
Immunohistochemistry-Paraffin: MCM6 Antibody [NB100-291]

Immunohistochemistry-Paraffin: MCM6 Antibody [NB100-291]

Immunohistochemistry-Paraffin: MCM6 Antibody [NB100-291] - Human breast carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-MCM6 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Applications for MCM6 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:000- 1:5000

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MCM6

MCM6 may be involved in the control of a single round of DNA replication during S phase. It binds to chromatin during G1 and detaches from it during S phase as if it licenses the chromatin to replicate.

Alternate Names

DNA replication licensing factor MCM6, EC 3.6.4.12, MCG40308, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S.cerevisiae), minichromosome maintenance complex component 6, minichromosome maintenance deficient (mis5, S. pombe) 6, minichromosome maintenance deficient 6 homolog, minichromosome maintenance deficient 6 homolog (S. cerevisiae), Mis5, MIS5 homolog, p105MCM

Entrez Gene IDs

4175 (Human)

Gene Symbol

MCM6

UniProt

NP_005906.2 (Human)

Additional MCM6 Products

Product Documents for MCM6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MCM6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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